The intravenous intralipid tolerance test.
نویسندگان
چکیده
The half-life of an intravenously injected bolus of intralipid 20% was measured in normal rats in order to asess its relationship to reticuloendothelial system (RES) activity. Groups of animals were studied following various treatments, and the results compared to measurement of carbon clearance in similar groups. The RES effects of silica and C parvum were confirmed by the carbon clearance test, but no effect was seen on the half-life of intralipid. Intralipid clearance was shortened by fasting and the administration of intravenous heparin, neither of which affected carbon clearance. It is concluded that the intravenous intralipid test has no place in the asessment of RES function.
منابع مشابه
Comparison of the Effects of Intralipid 10% and 20% on Peripheral Catheter Ablation in a Pediatric Intensive Care Unit
Background: Energy deficit is a common and serious problem in pediatric intensive care units. Parenteral nutrition, either alone or in combination with enteral nutrition, can improve nutrient delivery in critically ill patients by preventing or correcting the energy deficit and improving the outcomes. Intralipid 10% and 20% are lipid emulsions, widely used in parenteral nutrition. Despite sever...
متن کاملChanges of Total Plasma Triglycerides in Neonates Treated With Intralipid: A Pilot Study
The current scientific literature states that Intralipid 10% emulsion has a higher ratio of phospholipids to triglycerides, and contains more lypozomal phospholipids as compared to Intralipid 20% and Intralipid 30%, so it causes higher plasma concentrations of triglycerides, cholesterol and phospholipids (1, 2). It should be noted that serum triglycerides concentration is used as a marker for l...
متن کاملReversal of Cardiovascular Toxicity in Severe Organophosphate Poisoning with 20% Intralipid Emulsion Therapy: Case Report and Review of Literature
Background: Cardiac toxicity is one of the life-threatening effects of severe organophosphate (OP) poisoning. We presented a patient with severe OP poisoning, in cardiovascular shock poorly responsive to conventional treatments, who could be resuscitated successfully with intravenous lipid emulsion (ILE) therapy. Case report: A 26-year-old female was admitted to our emergency department who had...
متن کاملEffects of Multiple Infusions of a Fat Emulsion on Blood Coagulation, Liver Function and Urinary Excretion of Steroids in Schizophrenic Patients.
Preface 1 JOHN F. MUELLER AND LT. COL. JOHN E. CANHAM Analysis of Intravenous Fat Emulsions and Components 4 ARTHUR ROSE, NICHOLAS PELICK, F. M. ANGELONI AND M. E. MILLER Characterized Oils for Use in Intravenous Fat Emulsions 16 W. S. SINGLETON Studies on a Transparent and Concentrated Fat Emulsion for Intravenous Use . . 23 E. B. MCQUARRIE AND H. P. ANDERSEN Toxicity Testing of Fat Emulsions....
متن کاملThe Effects of Lipid Emulsion on the Improvement of Glasgow Coma Scale and Reduction of Blood Glucose Level in the Setting of Acute Non-Local Drug Poisoning: A Randomized Controlled Trial
Background: Our aim was to evaluate the effect of intravenous intralipid administration as an antidote on the poisoned patients' Glasgow Coma Scale (GCS), hemodynamic parameters, arterial blood gas analysis, and routine metabolic profile tests (i.e. urea, glucose, sodium, and potassium) in the setting of non-local anesthetic drug overdose. Methods: In this randomized controlled trial, a tota...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
- Journal of leukocyte biology
دوره 36 5 شماره
صفحات -
تاریخ انتشار 1984